Karl Arao has written a nice blog entry where he used also some of my tools for visualizing and understanding performance of a RAC cluster suddenly gone slow. He presents a systematic approach he used for gathering evidence and also hopefully you notice that having the ability to easily visualize performance data (with PerfSheet for example) can be very helpful and time saving when troubleshooting non-trivial problems.
Check his blog entry out here:
NB! I am running one more Advanced Oracle Troubleshooting training in 2018! You can attend the live online training and can download personal video recordings too. The Part 1 starts on 29th January 2018 - sign up here!